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Designing allosteric modulators for active conformational state of m-glutamate G-protein coupled receptors
G-protein coupled receptors (GPCRs) are found to be attractive drug targets for the treatment of various neuronal diseases. Allosteric modulators have their role in enhancing or suppressing the effect of glutamate on mGluRs. Structure of mGluR1 was generated with the help of Modeller software by con...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Biomedical Informatics
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3301996/ https://www.ncbi.nlm.nih.gov/pubmed/22419835 http://dx.doi.org/10.6026/97320630008170 |