Modulating Anti-MicroRNA-21 Activity and Specificity Using Oligonucleotide Derivatives and Length Optimization

MicroRNAs are short, endogenous RNAs that direct posttranscriptional regulation of gene expression vital for many developmental and cellular functions. Implicated in the pathogenesis of several human diseases, this group of RNAs provides interesting targets for therapeutic intervention. Anti-microRN...

Descripción completa

Detalles Bibliográficos
Autores principales: Muñoz-Alarcón, Andrés, Guterstam, Peter, Romero, Cristian, Behlke, Mark A., Lennox, Kim A., Wengel, Jesper, EL Andaloussi, Samir, Langel, Ülo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302052/
https://www.ncbi.nlm.nih.gov/pubmed/22474606
http://dx.doi.org/10.5402/2012/407154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302052/
https://www.ncbi.nlm.nih.gov/pubmed/22474606
http://dx.doi.org/10.5402/2012/407154

Ejemplares similares