Metformin mitigates the impaired development of skeletal muscle in the offspring of obese mice

Background: Maternal obesity is linked with offspring obesity and type 2 diabetes. Skeletal muscle (SM) insulin resistance is central to the development of diabetes. Adenosine monophosphate (AMP)-activated protein kinase (AMPK) is inhibited in SM of fetuses born to obese mothers. Objective: The aim...

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Detalles Bibliográficos
Autores principales: Tong, J F, Yan, X, Zhao, J X, Zhu, M J, Nathanielsz, P W, Du, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302133/
https://www.ncbi.nlm.nih.gov/pubmed/23449382
http://dx.doi.org/10.1038/nutd.2011.3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302133/
https://www.ncbi.nlm.nih.gov/pubmed/23449382
http://dx.doi.org/10.1038/nutd.2011.3

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