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Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection

The molecular mechanisms that drive mucosal T helper type 2 (T(H)2) responses against parasitic helminths and allergens remain unclear. In this study, we demonstrate in mice that TFF2 (trefoil factor 2), an epithelial cell–derived repair molecule, is needed for the control of lung injury caused by t...

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Detalles Bibliográficos
Autores principales: Wills-Karp, Marsha, Rani, Reena, Dienger, Krista, Lewkowich, Ian, Fox, James G., Perkins, Charles, Lewis, Lauren, Finkelman, Fred D., Smith, Dirk E., Bryce, Paul J., Kurt-Jones, Evelyn A., Wang, Timothy C., Sivaprasad, Umasundari, Hershey, Gurjit K., Herbert, De’Broski R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302229/
https://www.ncbi.nlm.nih.gov/pubmed/22329990
http://dx.doi.org/10.1084/jem.20110079