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Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection
The molecular mechanisms that drive mucosal T helper type 2 (T(H)2) responses against parasitic helminths and allergens remain unclear. In this study, we demonstrate in mice that TFF2 (trefoil factor 2), an epithelial cell–derived repair molecule, is needed for the control of lung injury caused by t...
Autores principales: | Wills-Karp, Marsha, Rani, Reena, Dienger, Krista, Lewkowich, Ian, Fox, James G., Perkins, Charles, Lewis, Lauren, Finkelman, Fred D., Smith, Dirk E., Bryce, Paul J., Kurt-Jones, Evelyn A., Wang, Timothy C., Sivaprasad, Umasundari, Hershey, Gurjit K., Herbert, De’Broski R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302229/ https://www.ncbi.nlm.nih.gov/pubmed/22329990 http://dx.doi.org/10.1084/jem.20110079 |
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