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Primary Epstein-Barr virus infection does not erode preexisting CD8(+) T cell memory in humans

Acute Epstein-Barr virus (EBV) infection results in an unusually robust CD8(+) T cell response in young adults. Based on mouse studies, such a response would be predicted to result in attrition of preexisting memory to heterologous infections like influenza A (Flu) and cytomegalovirus (CMV). Further...

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Detalles Bibliográficos
Autores principales: Odumade, Oludare A., Knight, Jennifer A., Schmeling, David O., Masopust, David, Balfour, Henry H., Hogquist, Kristin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302231/
https://www.ncbi.nlm.nih.gov/pubmed/22393125
http://dx.doi.org/10.1084/jem.20112401