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TGF-β synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growth

Malignant mesothelioma (MM) is an incurable malignancy that is caused by exposure to asbestos and is accompanied by severe fibrosis. Because MM is usually diagnosed at an advanced stage and clinical identification of early lesions is difficult, its molecular pathogenesis has not been completely eluc...

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Detalles Bibliográficos
Autores principales: Fujii, Makiko, Toyoda, Takeshi, Nakanishi, Hayao, Yatabe, Yasushi, Sato, Ayuko, Matsudaira, Yasue, Ito, Hidemi, Murakami, Hideki, Kondo, Yutaka, Kondo, Eisaku, Hida, Toyoaki, Tsujimura, Tohru, Osada, Hirotaka, Sekido, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302232/
https://www.ncbi.nlm.nih.gov/pubmed/22329991
http://dx.doi.org/10.1084/jem.20111653