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TGF-β synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growth
Malignant mesothelioma (MM) is an incurable malignancy that is caused by exposure to asbestos and is accompanied by severe fibrosis. Because MM is usually diagnosed at an advanced stage and clinical identification of early lesions is difficult, its molecular pathogenesis has not been completely eluc...
Autores principales: | Fujii, Makiko, Toyoda, Takeshi, Nakanishi, Hayao, Yatabe, Yasushi, Sato, Ayuko, Matsudaira, Yasue, Ito, Hidemi, Murakami, Hideki, Kondo, Yutaka, Kondo, Eisaku, Hida, Toyoaki, Tsujimura, Tohru, Osada, Hirotaka, Sekido, Yoshitaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302232/ https://www.ncbi.nlm.nih.gov/pubmed/22329991 http://dx.doi.org/10.1084/jem.20111653 |
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