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Autocrine VEGF–VEGFR2–Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

Although vascular endothelial growth factor (VEGF) receptor 2 (VEGFR2) is traditionally regarded as an endothelial cell protein, evidence suggests that VEGFRs may be expressed by cancer cells. Glioblastoma multiforme (GBM) is a lethal cancer characterized by florid vascularization and aberrantly ele...

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Detalles Bibliográficos
Autores principales: Hamerlik, Petra, Lathia, Justin D., Rasmussen, Rikke, Wu, Qiulian, Bartkova, Jirina, Lee, MyungHee, Moudry, Pavel, Bartek, Jiri, Fischer, Walter, Lukas, Jiri, Rich, Jeremy N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302235/
https://www.ncbi.nlm.nih.gov/pubmed/22393126
http://dx.doi.org/10.1084/jem.20111424