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SARS-CoV heptad repeat 2 is a trimer of parallel helices

In severe acute respiratory syndrome coronavirus, the envelope heptad repeat 2 (HR2) plays a critical role in viral entry. Moreover, HR2 is both the target for novel antiviral therapies and, as an isolated peptide, presents a potential antiviral therapeutic. The structure of HR2, as determined by NM...

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Detalles Bibliográficos
Autores principales: Celigoy, Jessica, Ramirez, Benjamin, Caffrey, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302656/
https://www.ncbi.nlm.nih.gov/pubmed/21922588
http://dx.doi.org/10.1002/pro.736