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Chk1 and Wee1 kinases coordinate DNA replication, chromosome condensation, and anaphase entry

Defects in DNA replication and chromosome condensation are common phenotypes in cancer cells. A link between replication and condensation has been established, but little is known about the role of checkpoints in monitoring chromosome condensation. We investigate this function by live analysis, usin...

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Detalles Bibliográficos
Autores principales: Fasulo, Barbara, Koyama, Carol, Yu, Kristina R., Homola, Ellen M., Hsieh, Tao S., Campbell, Shelagh D., Sullivan, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302732/
https://www.ncbi.nlm.nih.gov/pubmed/22262459
http://dx.doi.org/10.1091/mbc.E11-10-0832