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Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions

Ubiquitination is a reversible modification that influences a broad range of physiological processes. There are approximately 90 deubiquitinases (DUBs) encoded in the human genome, of which 79 are predicted to have catalytic activity. We tagged 66 DUBs with green fluorescent protein and systematical...

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Detalles Bibliográficos
Autores principales: Urbé, Sylvie, Liu, Han, Hayes, Sebastian D., Heride, Claire, Rigden, Daniel J., Clague, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302736/
https://www.ncbi.nlm.nih.gov/pubmed/22298430
http://dx.doi.org/10.1091/mbc.E11-08-0668