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Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions
Ubiquitination is a reversible modification that influences a broad range of physiological processes. There are approximately 90 deubiquitinases (DUBs) encoded in the human genome, of which 79 are predicted to have catalytic activity. We tagged 66 DUBs with green fluorescent protein and systematical...
Autores principales: | Urbé, Sylvie, Liu, Han, Hayes, Sebastian D., Heride, Claire, Rigden, Daniel J., Clague, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302736/ https://www.ncbi.nlm.nih.gov/pubmed/22298430 http://dx.doi.org/10.1091/mbc.E11-08-0668 |
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