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The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2

The mammalian cell nucleus is functionally compartmentalized into various substructures. Nuclear speckles, also known as interchromatin granule clusters, are enriched with SR splicing factors and are implicated in gene expression. Here we report that nuclear speckle formation is developmentally regu...

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Detalles Bibliográficos
Autores principales: Saitoh, Noriko, Sakamoto, Chiyomi, Hagiwara, Masatoshi, Agredano-Moreno, Lourdes T., Jiménez-García, Luis Felipe, Nakao, Mitsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302738/
https://www.ncbi.nlm.nih.gov/pubmed/22262462
http://dx.doi.org/10.1091/mbc.E11-09-0783