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Phosphorylation-dependent 14-3-3 protein interactions regulate CFTR biogenesis

Cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP/protein kinase A (PKA)–regulated chloride channel whose phosphorylation controls anion secretion across epithelial cell apical membranes. We examined the hypothesis that cAMP/PKA stimulation regulates CFTR biogenesis posttranslatio...

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Detalles Bibliográficos
Autores principales: Liang, Xiubin, Da Paula, Ana Carina, Bozóky, Zoltán, Zhang, Hui, Bertrand, Carol A., Peters, Kathryn W., Forman-Kay, Julie D., Frizzell, Raymond A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302758/
https://www.ncbi.nlm.nih.gov/pubmed/22278744
http://dx.doi.org/10.1091/mbc.E11-08-0662