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Constitutive Expression of TNF-Related Activation-Induced Cytokine (TRANCE)/Receptor Activating NF-κB Ligand (RANK)-L by Rat Plasmacytoid Dendritic Cells

Plasmacytoid dendritic cells (pDCs) are a subset of DCs whose major function relies on their capacity to produce large amount of type I IFN upon stimulation via TLR 7 and 9. This function is evolutionary conserved and place pDC in critical position in the innate immune response to virus. Here we sho...

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Detalles Bibliográficos
Autores principales: Anjubault, Thomas, Martin, Jérôme, Hubert, François-Xavier, Chauvin, Camille, Heymann, Dominique, Josien, Régis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302772/
https://www.ncbi.nlm.nih.gov/pubmed/22428075
http://dx.doi.org/10.1371/journal.pone.0033713