Inhibition of Melanogenesis by the Pyridinyl Imidazole Class of Compounds: Possible Involvement of the Wnt/β-Catenin Signaling Pathway

While investigating the role of p38 MAPK in regulating melanogenesis, we found that pyridinyl imidazole inhibitors class compounds as well as the analog compound SB202474, which does not inhibit p38 MAPK, suppressed both α-MSH-induced melanogenesis and spontaneous melanin synthesis. In this study, w...

Descripción completa

Detalles Bibliográficos
Autores principales: Bellei, Barbara, Pitisci, Angela, Izzo, Enzo, Picardo, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302780/
https://www.ncbi.nlm.nih.gov/pubmed/22427932
http://dx.doi.org/10.1371/journal.pone.0033021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302780/
https://www.ncbi.nlm.nih.gov/pubmed/22427932
http://dx.doi.org/10.1371/journal.pone.0033021

Ejemplares similares