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Cellular Phenotype-Dependent and -Independent Effects of Vitamin C on the Renewal and Gene Expression of Mouse Embryonic Fibroblasts

Vitamin C has been shown to delay the cellular senescence and was considered a candidate for chemoprevention and cancer therapy. To understand the reported contrasting roles of vitamin C: growth-promoting in the primary cells and growth-inhibiting in cancer cells, primary mouse embryonic fibroblasts...

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Detalles Bibliográficos
Autores principales: Kuo, Shiu-Ming, Burl, Lana R., Hu, Zihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302785/
https://www.ncbi.nlm.nih.gov/pubmed/22427916
http://dx.doi.org/10.1371/journal.pone.0032957