The JNK Inhibitor XG-102 Protects against TNBS-Induced Colitis

The c-Jun N-terminal kinase (JNK)-inhibiting peptide D-JNKI-1, syn. XG-102 was tested for its therapeutic potential in acute inflammatory bowel disease (IBD) in mice. Rectal instillation of the chemical irritant trinitrobenzene sulfonic acid (TNBS) provoked a dramatic acute inflammation in the colon...

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Detalles Bibliográficos
Autores principales: Reinecke, Kirstin, Eminel, Sevgi, Dierck, Franziska, Roessner, Wibke, Kersting, Sabine, Chromik, Ansgar Michael, Gavrilova, Olga, Laukevicience, Ale, Leuschner, Ivo, Waetzig, Vicki, Rosenstiel, Philip, Herdegen, Thomas, Sina, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302790/
https://www.ncbi.nlm.nih.gov/pubmed/22427801
http://dx.doi.org/10.1371/journal.pone.0030985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302790/
https://www.ncbi.nlm.nih.gov/pubmed/22427801
http://dx.doi.org/10.1371/journal.pone.0030985

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