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Speed-Dependent Cellular Decision Making in Nonequilibrium Genetic Circuits

Despite being governed by the principles of nonequilibrium transitions, gene expression dynamics underlying cell fate decision is poorly understood. In particular, the effect of signaling speed on cellular decision making is still unclear. Here we show that the decision between alternative cell fate...

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Detalles Bibliográficos
Autores principales: Nené, Nuno R., Garca-Ojalvo, Jordi, Zaikin, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302799/
https://www.ncbi.nlm.nih.gov/pubmed/22427883
http://dx.doi.org/10.1371/journal.pone.0032779