Enhanced Protective Efficacy of a Chimeric Form of the Schistosomiasis Vaccine Antigen Sm-TSP-2

The large extracellular loop of the Schistosoma mansoni tetraspanin, Sm-TSP-2, when fused to a thioredoxin partner and formulated with Freund's adjuvants, has been shown to be an efficacious vaccine against murine schistosomiasis. Moreover, Sm-TSP-2 is uniquely recognised by IgG(1) and IgG(3) f...

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Detalles Bibliográficos
Autores principales: Pearson, Mark S., Pickering, Darren A., McSorley, Henry J., Bethony, Jeffrey M., Tribolet, Leon, Dougall, Annette M., Hotez, Peter J., Loukas, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302818/
https://www.ncbi.nlm.nih.gov/pubmed/22428079
http://dx.doi.org/10.1371/journal.pntd.0001564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302818/
https://www.ncbi.nlm.nih.gov/pubmed/22428079
http://dx.doi.org/10.1371/journal.pntd.0001564

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