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Convergent Evolution of Escape from Hepaciviral Antagonism in Primates
The ability to mount an interferon response on sensing viral infection is a critical component of mammalian innate immunity. Several viruses directly antagonize viral sensing pathways to block activation of the host immune response. Here, we show that recurrent viral antagonism has shaped the evolut...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302847/ https://www.ncbi.nlm.nih.gov/pubmed/22427742 http://dx.doi.org/10.1371/journal.pbio.1001282 |