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Convergent Evolution of Escape from Hepaciviral Antagonism in Primates

The ability to mount an interferon response on sensing viral infection is a critical component of mammalian innate immunity. Several viruses directly antagonize viral sensing pathways to block activation of the host immune response. Here, we show that recurrent viral antagonism has shaped the evolut...

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Detalles Bibliográficos
Autores principales: Patel, Maulik R., Loo, Yueh-Ming, Horner, Stacy M., Gale, Michael, Malik, Harmit S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302847/
https://www.ncbi.nlm.nih.gov/pubmed/22427742
http://dx.doi.org/10.1371/journal.pbio.1001282

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