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Cell-Autonomous Alterations in Dendritic Arbor Morphology and Connectivity Induced by Overexpression of MeCP2 in Xenopus Central Neurons In Vivo

Methyl CpG binding protein-2 (MeCP2) is an essential epigenetic regulator in human brain development. Mutations in the MeCP2 gene have been linked to Rett syndrome, a severe X-linked progressive neurodevelopmental disorder, and one of the most common causes of mental retardation in females. MeCP2 du...

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Detalles Bibliográficos
Autores principales: Marshak, Sonya, Meynard, Margarita M., De Vries, Ymkje A., Kidane, Adhanet H., Cohen-Cory, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302857/
https://www.ncbi.nlm.nih.gov/pubmed/22427975
http://dx.doi.org/10.1371/journal.pone.0033153