Cysteinyl-tRNA Deacylation Can Be Uncoupled from Protein Synthesis

Aminoacyl-tRNA synthetases (ARSs) are critical components of protein translation, providing ribosomes with aminoacyl-tRNAs. In return, ribosomes release uncharged tRNAs as ARS substrates. Here, we show that tRNA deacylation can be uncoupled from protein synthesis in an amino acid specific manner. Wh...

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Detalles Bibliográficos
Autores principales: David, Alexandre, Das, Suman R., Gibbs, James S., Bennink, Jack R., Yewdell, Jonathan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302863/
https://www.ncbi.nlm.nih.gov/pubmed/22427952
http://dx.doi.org/10.1371/journal.pone.0033072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302863/
https://www.ncbi.nlm.nih.gov/pubmed/22427952
http://dx.doi.org/10.1371/journal.pone.0033072

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