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Cysteinyl-tRNA Deacylation Can Be Uncoupled from Protein Synthesis
Aminoacyl-tRNA synthetases (ARSs) are critical components of protein translation, providing ribosomes with aminoacyl-tRNAs. In return, ribosomes release uncharged tRNAs as ARS substrates. Here, we show that tRNA deacylation can be uncoupled from protein synthesis in an amino acid specific manner. Wh...
Autores principales: | David, Alexandre, Das, Suman R., Gibbs, James S., Bennink, Jack R., Yewdell, Jonathan W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302863/ https://www.ncbi.nlm.nih.gov/pubmed/22427952 http://dx.doi.org/10.1371/journal.pone.0033072 |
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