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Uncovering the Molecular Machinery of the Human Spindle—An Integration of Wet and Dry Systems Biology

The mitotic spindle is an essential molecular machine involved in cell division, whose composition has been studied extensively by detailed cellular biology, high-throughput proteomics, and RNA interference experiments. However, because of its dynamic organization and complex regulation it is diffic...

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Detalles Bibliográficos
Autores principales: Rojas, Ana M., Santamaria, Anna, Malik, Rainer, Jensen, Thomas Skøt, Körner, Roman, Morilla, Ian, de Juan, David, Krallinger, Martin, Hansen, Daniel Aaen, Hoffmann, Robert, Lees, Jonathan, Reid, Adam, Yeats, Corin, Wehner, Anja, Elowe, Sabine, Clegg, Andrew B., Brunak, Søren, Nigg, Erich A., Orengo, Christine, Valencia, Alfonso, Ranea, Juan A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302876/
https://www.ncbi.nlm.nih.gov/pubmed/22427808
http://dx.doi.org/10.1371/journal.pone.0031813