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CACNA1E Variants Affect Beta Cell Function in Patients with Newly Diagnosed Type 2 Diabetes. The Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 3

BACKGROUND: Genetic variability of the major subunit (CACNA1E) of the voltage-dependent Ca(2+) channel Ca(V)2.3 is associated to risk of type 2 diabetes, insulin resistance and impaired insulin secretion in nondiabetic subjects. The aim of the study was to test whether CACNA1E common variability aff...

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Detalles Bibliográficos
Autores principales: Trombetta, Maddalena, Bonetti, Sara, Boselli, MariaLinda, Turrini, Fabiola, Malerba, Giovanni, Trabetti, Elisabetta, Pignatti, PierFranco, Bonora, Enzo, Bonadonna, Riccardo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302892/
https://www.ncbi.nlm.nih.gov/pubmed/22427875
http://dx.doi.org/10.1371/journal.pone.0032755