Chronic Allergic Inflammation Causes Vascular Remodeling and Pulmonary Hypertension in Bmpr2 Hypomorph and Wild-Type Mice

Loss-of-function mutations in the bone morphogenetic protein receptor type 2 (BMPR2) gene have been identified in patients with heritable pulmonary arterial hypertension (PAH); however, disease penetrance is low, suggesting additional factors play a role. Inflammation is associated with PAH and vasc...

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Detalles Bibliográficos
Autores principales: Mushaben, Elizabeth M., Hershey, Gurjit Khurana, Pauciulo, Michael W., Nichols, William C., Le Cras, Timothy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302893/
https://www.ncbi.nlm.nih.gov/pubmed/22427841
http://dx.doi.org/10.1371/journal.pone.0032468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302893/
https://www.ncbi.nlm.nih.gov/pubmed/22427841
http://dx.doi.org/10.1371/journal.pone.0032468

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