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A positive feedback loop between HER2 and ADAM12 in human head and neck cancer cells increases migration and invasion

Increased activation of epidermal growth factor receptor (EGFR) family members such as HER2/Erbb2 can result in more aggressive disease, resistance to chemotherapy and reduced survival of head and neck squamous cell carcinoma (HNSCC) patients. In order to identify mechanisms through which these rece...

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Detalles Bibliográficos
Autores principales: Rao, Velidi H., Kandel, Amrit, Lynch, Dave, Pena, Zachary, Marwaha, Nitin, Deng, Caishu, Watson, Patrice, Hansen, Laura A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302945/
https://www.ncbi.nlm.nih.gov/pubmed/21986939
http://dx.doi.org/10.1038/onc.2011.460