Myostatin blockage using actRIIB antagonism in mice bearing the Lewis lung carcinoma results in the improvement of muscle wasting and physical performance

BACKGROUND: Cachexia is a multiorganic syndrome associated with cancer, characterized by body weight loss, muscle and adipose tissue wasting and inflammation. METHODS: The aim of this investigation was to examine the effect of the soluble receptor antagonist of myostatin (sActRIIB) in cachectic tumo...

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Detalles Bibliográficos
Autores principales: Busquets, Sílvia, Toledo, Míriam, Orpí, Marcel, Massa, David, Porta, Maria, Capdevila, Eva, Padilla, Núria, Frailis, Valentina, López-Soriano, Francisco J., Han, H. Q., Argilés, Josep M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302990/
https://www.ncbi.nlm.nih.gov/pubmed/22450815
http://dx.doi.org/10.1007/s13539-011-0049-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302990/
https://www.ncbi.nlm.nih.gov/pubmed/22450815
http://dx.doi.org/10.1007/s13539-011-0049-z

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