High-throughput decoding of anti-trypanosomal drug efficacy and resistance

The concept of specific chemotherapy was developed a century ago by Paul Ehrlich and others. Dyes and arsenical compounds that displayed selectivity against trypanosomes were central to this work (1,2), and the drugs that emerged remain in use for treating Human African Trypanosomiasis (HAT) (3). Eh...

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Detalles Bibliográficos
Autores principales: Alsford, Sam, Eckert, Sabine, Baker, Nicola, Glover, Lucy, Sanchez-Flores, Alejandro, Leung, Ka Fai, Turner, Daniel J., Field, Mark C., Berriman, Matthew, Horn, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303116/
https://www.ncbi.nlm.nih.gov/pubmed/22278056
http://dx.doi.org/10.1038/nature10771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303116/
https://www.ncbi.nlm.nih.gov/pubmed/22278056
http://dx.doi.org/10.1038/nature10771

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