Periodic stripe formation by a Turing-mechanism operating at growth zones in the mammalian palate

We present direct evidence of an activator-inhibitor system in the generation of the regularly spaced transverse ridges of the palate. We show that new ridges, or rugae, marked by stripes of Sonic hedgehog (Shh) expression, appear at two growth zones where the space between previously laid-down ruga...

Descripción completa

Detalles Bibliográficos
Autores principales: Economou, Andrew D., Ohazama, Atsushi, Porntaveetus, Thantrira, Sharpe, Paul T., Kondo, Shigeru, Basson, M. Albert, Gritli-Linde, Amel, Cobourne, Martyn T., Green, Jeremy B.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303118/
https://www.ncbi.nlm.nih.gov/pubmed/22344222
http://dx.doi.org/10.1038/ng.1090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303118/
https://www.ncbi.nlm.nih.gov/pubmed/22344222
http://dx.doi.org/10.1038/ng.1090

Ejemplares similares