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Differential confounding of rare and common variants in spatially structured populations
Well-powered genome-wide association studies, now possible through advances in technology and large-scale collaborative projects, promise to reveal the contribution of rare variants to complex traits and disease. However, while population structure is a known confounder of association studies, it is...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303124/ https://www.ncbi.nlm.nih.gov/pubmed/22306651 http://dx.doi.org/10.1038/ng.1074 |