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Strong physical constraints on sequence-specific target location by proteins on DNA molecules
Sequence-specific binding to DNA in the presence of competing non-sequence-specific ligands is a problem faced by proteins in all organisms. It is akin to the problem of parking a truck at a loading bay by the side of a road in the presence of cars parked at random along the road. Cars even partiall...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303175/ https://www.ncbi.nlm.nih.gov/pubmed/16698961 http://dx.doi.org/10.1093/nar/gkl271 |