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Analysis of hypermethylation and expression profiles of APC and ATM genes in patients with oral squamous cell carcinoma

BACKGROUND: Adenomatous polyposis coli (APC) and Ataxia-telangiectasia-mutated (ATM) gene products have an important role in cell cycle control and maintenance of genomic stability. Our aim was to analyze ATM and APC methylation and its relationship with oral squamous cell carcinoma (OSCC). MATERIAL...

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Detalles Bibliográficos
Autores principales: Rigi-Ladiz, Mohammad Ayub, Kordi-Tamandani, Dor Mohammad, Torkamanzehi, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303468/
https://www.ncbi.nlm.nih.gov/pubmed/22414247
http://dx.doi.org/10.1186/1868-7083-3-6