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Analysis of hypermethylation and expression profiles of APC and ATM genes in patients with oral squamous cell carcinoma
BACKGROUND: Adenomatous polyposis coli (APC) and Ataxia-telangiectasia-mutated (ATM) gene products have an important role in cell cycle control and maintenance of genomic stability. Our aim was to analyze ATM and APC methylation and its relationship with oral squamous cell carcinoma (OSCC). MATERIAL...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303468/ https://www.ncbi.nlm.nih.gov/pubmed/22414247 http://dx.doi.org/10.1186/1868-7083-3-6 |