Suffocating cancer: hypoxia-associated epimutations as targets for cancer therapy

Lower than normal levels of oxygen (hypoxia) is a hallmark of all solid tumours rendering them frequently resistant to both radiotherapy and chemotherapy regimes. Furthermore, tumour hypoxia and activation of the hypoxia inducible factor (HIF) transcriptional pathway is associated with poorer progno...

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Detalles Bibliográficos
Autores principales: Thirlwell, C, Schulz, LKE, Dibra, HK, Beck, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303469/
https://www.ncbi.nlm.nih.gov/pubmed/22414300
http://dx.doi.org/10.1186/1868-7083-3-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303469/
https://www.ncbi.nlm.nih.gov/pubmed/22414300
http://dx.doi.org/10.1186/1868-7083-3-9

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