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Nevirapine-Based Antiretroviral Therapy Impacts Artesunate and Dihydroartemisinin Disposition in HIV-Infected Nigerian Adults

Background. Nevirapine- (NVP-) based antiretroviral therapy (ART) and artesunate-amodiaquine are frequently coprescribed in areas of HIV and malaria endemicity. We explored the impact of this practice on artesunate and dihydroartemisinin pharmacokinetics. Methods. We conducted a parallel-group pharm...

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Detalles Bibliográficos
Autores principales: Fehintola, Fatai A., Scarsi, Kimberly K., Ma, Qing, Parikh, Sunil, Morse, Gene D., Taiwo, Babafemi, Akinola, Ibrahim Tope, Adewole, Isaac F., Lindegardh, Niklas, Phakderaj, Aphiradee, Ojengbede, Oladosu, Murphy, Robert L., Akinyinka, Olusegun O., Aweeka, Francesca T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303559/
https://www.ncbi.nlm.nih.gov/pubmed/22500218
http://dx.doi.org/10.1155/2012/703604