Triiodothyronine Represses MUC5AC Expression by Antagonizing Sp1 Binding to Its Promoter in Human Bronchial Epithelial HBE16 Cells

Mucus hypersecretion is a distinguished feature of chronic inflammatory airway diseases. Interestingly, in this condition thyroid function is impaired with decreased level of triiodothyronine (T3), indicating potential link between low level of T3 and mucus hypersecretion. But the underlying mechani...

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Detalles Bibliográficos
Autores principales: Wang, Xiaolong, Li, Qi, Zhou, Xiangdong, Kolosov, Victor P., Perelman, Juliy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303580/
https://www.ncbi.nlm.nih.gov/pubmed/22500101
http://dx.doi.org/10.1155/2012/648170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303580/
https://www.ncbi.nlm.nih.gov/pubmed/22500101
http://dx.doi.org/10.1155/2012/648170

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