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Emergence of Exhausted B Cells in Asymptomatic HIV-1-Infected Patients Naïve for HAART is Related to Reduced Immune Surveillance

Alterations of B cell subpopulations have been described up to date as characterizing advanced stage of HIV-1 infection. However, whether such defects are relevant in subjects with a preserved number of CD4(+) T cells (>350 cells/μL) is unclear. In a cross-sectional study, we investigated if sign...

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Detalles Bibliográficos
Autores principales: Fogli, Manuela, Torti, Carlo, Malacarne, Fabio, Fiorentini, Simona, Albani, Melania, Izzo, Ilaria, Giagulli, Cinzia, Maggi, Fabrizio, Carosi, Giampiero, Caruso, Arnaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303688/
https://www.ncbi.nlm.nih.gov/pubmed/22474482
http://dx.doi.org/10.1155/2012/829584