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Accurate multiple sequence alignment of transmembrane proteins with PSI-Coffee
BACKGROUND: Transmembrane proteins (TMPs) constitute about 20~30% of all protein coding genes. The relative lack of experimental structure has so far made it hard to develop specific alignment methods and the current state of the art (PRALINE™) only manages to recapitulate 50% of the positions in th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303701/ https://www.ncbi.nlm.nih.gov/pubmed/22536955 http://dx.doi.org/10.1186/1471-2105-13-S4-S1 |