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Features of Methylation and Gene Expression in the Promoter-Associated CpG Islands Using Human Methylome Data

CpG islands are typically located in the 5′ end of genes and considered as gene markers because they play important roles in gene regulation via epigenetic change. In this study, we compared the features of CpG islands identified by several major algorithms by setting the parameter cutoff values in...

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Detalles Bibliográficos
Autores principales: Du, Xin, Han, Leng, Guo, An-Yuan, Zhao, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303704/
https://www.ncbi.nlm.nih.gov/pubmed/22474411
http://dx.doi.org/10.1155/2012/598987