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Features of Methylation and Gene Expression in the Promoter-Associated CpG Islands Using Human Methylome Data
CpG islands are typically located in the 5′ end of genes and considered as gene markers because they play important roles in gene regulation via epigenetic change. In this study, we compared the features of CpG islands identified by several major algorithms by setting the parameter cutoff values in...
Autores principales: | Du, Xin, Han, Leng, Guo, An-Yuan, Zhao, Zhongming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303704/ https://www.ncbi.nlm.nih.gov/pubmed/22474411 http://dx.doi.org/10.1155/2012/598987 |
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