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Effect of PGC-1α on Proliferation, Migration, and Transdifferentiation of Rat Vascular Smooth Muscle Cells Induced by High Glucose

We assessed the role of PGC-1α (PPARγ coactivator-1 alpha) in glucose-induced proliferation, migration, and inflammatory gene expression of vascular smooth muscle cells (VSMCs). We carried out phagocytosis studies to assess the role of PGC-1α in transdifferentiation of VSMCs by flow cytometry. We fo...

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Detalles Bibliográficos
Autores principales: Qi, Xiaoqiang, Zhang, Yujing, Li, Jing, Hou, Dongxia, Xiang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303719/
https://www.ncbi.nlm.nih.gov/pubmed/22461724
http://dx.doi.org/10.1155/2012/756426