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Prioritization of pathogenic mutations in the protein kinase superfamily
BACKGROUND: Most of the many mutations described in human protein kinases are tolerated without significant disruption of the corresponding structures or molecular functions, while some of them have been associated to a variety of human diseases, including cancer. In the last decade, a plethora of c...
Autores principales: | Izarzugaza, Jose MG, del Pozo, Angela, Vazquez, Miguel, Valencia, Alfonso |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303724/ https://www.ncbi.nlm.nih.gov/pubmed/22759651 http://dx.doi.org/10.1186/1471-2164-13-S4-S3 |
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