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Early Interleukin-6 and Slope of Monocyte Human Leukocyte Antigen-DR: A Powerful Association to Predict the Development of Sepsis after Major Trauma

OBJECTIVE: Major trauma is characterized by a pro-inflammatory response, followed by an immunosuppression. Recently, in trauma patients, the lack of recovery of monocyte Human Leukocyte Antigen DR (mHLA-DR, a biomarker of ICU-acquired immunosuppression) between days 1–2 and days 3–4 has been demonst...

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Detalles Bibliográficos
Autores principales: Gouel-Chéron, Aurélie, Allaouchiche, Bernard, Guignant, Caroline, Davin, Fanny, Floccard, Bernard, Monneret, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303782/
https://www.ncbi.nlm.nih.gov/pubmed/22431998
http://dx.doi.org/10.1371/journal.pone.0033095