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A Cell-Based Small Molecule Screening Method for Identifying Inhibitors of Epithelial-Mesenchymal Transition in Carcinoma

Epithelial Mesenchymal Transition (EMT) is a crucial mechanism for carcinoma progression, as it provides routes for in situ carcinoma cells to dissociate and become motile, leading to localized invasion and metastatic spread. Targeting EMT therefore represents an important therapeutic strategy for c...

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Detalles Bibliográficos
Autores principales: Chua, Kian-Ngiap, Sim, Wen-Jing, Racine, Victor, Lee, Shi-Yun, Goh, Boon Cher, Thiery, Jean Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303807/
https://www.ncbi.nlm.nih.gov/pubmed/22432005
http://dx.doi.org/10.1371/journal.pone.0033183