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A Cell-Based Small Molecule Screening Method for Identifying Inhibitors of Epithelial-Mesenchymal Transition in Carcinoma
Epithelial Mesenchymal Transition (EMT) is a crucial mechanism for carcinoma progression, as it provides routes for in situ carcinoma cells to dissociate and become motile, leading to localized invasion and metastatic spread. Targeting EMT therefore represents an important therapeutic strategy for c...
Autores principales: | Chua, Kian-Ngiap, Sim, Wen-Jing, Racine, Victor, Lee, Shi-Yun, Goh, Boon Cher, Thiery, Jean Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303807/ https://www.ncbi.nlm.nih.gov/pubmed/22432005 http://dx.doi.org/10.1371/journal.pone.0033183 |
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