Cargando…

In Vitro Aggregation Behavior of a Non-Amyloidogenic λ Light Chain Dimer Deriving from U266 Multiple Myeloma Cells

Excessive production of monoclonal light chains due to multiple myeloma can induce aggregation-related disorders, such as light chain amyloidosis (AL) and light chain deposition diseases (LCDD). In this work, we produce a non-amyloidogenic IgE λ light chain dimer from human mammalian cells U266, whi...

Descripción completa

Detalles Bibliográficos
Autores principales: Arosio, Paolo, Owczarz, Marta, Müller-Späth, Thomas, Rognoni, Paola, Beeg, Marten, Wu, Hua, Salmona, Mario, Morbidelli, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303827/
https://www.ncbi.nlm.nih.gov/pubmed/22432016
http://dx.doi.org/10.1371/journal.pone.0033372