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In Vitro Aggregation Behavior of a Non-Amyloidogenic λ Light Chain Dimer Deriving from U266 Multiple Myeloma Cells

Excessive production of monoclonal light chains due to multiple myeloma can induce aggregation-related disorders, such as light chain amyloidosis (AL) and light chain deposition diseases (LCDD). In this work, we produce a non-amyloidogenic IgE λ light chain dimer from human mammalian cells U266, whi...

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Detalles Bibliográficos
Autores principales:	Arosio, Paolo, Owczarz, Marta, Müller-Späth, Thomas, Rognoni, Paola, Beeg, Marten, Wu, Hua, Salmona, Mario, Morbidelli, Massimo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303827/ https://www.ncbi.nlm.nih.gov/pubmed/22432016 http://dx.doi.org/10.1371/journal.pone.0033372

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